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This deterioration of GSH homeostasis is in conjunction with other physiological events, in the ageing process and the appearance of age-related diseases
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AGEs not only suppress eNOS expression but also trigger oxidative stress via the MAPK/ERK pathways [77, 78] While largely inactive under normal conditions, hyperglycemia activates the polyol pathway in ECs, leading to detrimental consequences [79]
BAC can be up to 3 higher than a comparable drinker who ate beforehand
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