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As a stabilized analog it resists the enzyme (dipeptidyl peptidase-4) that rapidly chews up native GHRH, so its push lasts longer and the resulting pulse is larger and more durable than the bodys own

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"Safety Alerts for Human Medical Products - Diabetes Medications Containing Saxagliptin and Alogliptin: Drug Safety Communication - Risk of Heart Failure"

Zhang, Y., An, S., Hao, J., Tian, F., Fang, X., & Wang, J

At GLP-1R, EC50 values for cAMP accumulation are in the low nanomolar range