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Results Cigarette smoke in APP/PS1 increases blood cotinine levels APP/PS1 transgenic mice were exposed to both mainstream (smoke inhaled by an active smoker) and sidestream smoke (smoke from the burning end of a cigarette) in a non-ventilated exposure chamber, using a peristaltic pump that sucked the smoke from the cigarette with an airflow rate of 80 ml min 1 (Fig

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