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IGF-1 LR3 (IGF-1 long R3) is a fusion protein that include in the amino terminus the first 11 amino acids of methionyl porcine growth hormone and the IGF1 sequence, where Glu3 was substituted by Arg
Li Y, Tang ZY, Ye SL, Liu YK, Chen J, Xue Q, et al
Their advocacy for GLP1 accessibility is unmatched
This change likely affects activity-dependent myelination in the aged brain by significantly impacting the ability for OPCs to sense and act on glutamate released from active neurons (Gautier et al., 2015
On top of this, they also possess antioxidant properties, which help fight off the damage caused by free radicals and the stress of modern life
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