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According to Patni et al

They work by activating GLP1 receptors in the body to increase insulin release from the pancreatic beta-cells, decrease the breakdown of glucose stores from the liver, and slow gastric emptying.[6,8,10,11] Additionally, semaglutide can affect appetite and caloric intake by involving different pathways in the brain.[11] Safety Information The side effects between dulaglutide and semaglutide are similar.[6,8,10,11] The most common side effects seen in patients taking either medication are nausea, diarrhea, vomiting, and abdominal pain

They're a clinical intervention

Several of the city's best providers now do most follow-ups virtually, with in-person visits only when you need bloodwork or body composition testing