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Inborn errors of metabolism (e.g., vitamin B6-dependent convulsions or B6-responsive anemia)

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Oral tablets eliminate needle-related bruising entirely, though they typically require higher doses and may have different absorption patterns

12 Based on current cardiovascular outcome data such as that provided in SUSTAIN-6, the American Diabetes Association (ADA) now recommends GLP-1 receptor agonists with proven cardiovascular benefit as a preferred option for second-line add-on therapy in patients with T2DM and established atherosclerotic cardiovascular disease (ASCVD) following metformin and lifestyle-change intensification