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A system that converts existing antibodies into intracellular tools could have applications far beyond neurodegenerative disease, including cancer biology, inflammatory disorders and rare genetic conditions

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After cryoprotection, the brainstem was separated and cut on a cryostat (Leica 1800) into 18 m coronal sections, which were mounted on microscope slides (SuperFrost Ultra Plus GOLD), for later imaging using fluorescence microscopy

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