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Both agents target glucose homeostasis through different mechanismsberberine activates AMPK and improves insulin sensitivity, while GLP-1 agonists enhance insulin secretion and slow gastric emptying, creating potential synergy rather than direct antagonism

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Nevertheless, drug-induced pigmentation has not been reported to undergo malignant transformation [14,15]

Description A multi-component research material supplied for controlled research environments

doi: 10.1016/j.freeradbiomed.2023.12.031 312 FangLYanYXuZHeZZhouSJiangXet al