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Validation To validate predictions of the model we used publicly available data that were not used to construct the model

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Subcutaneous injections are administered into fat under the skin, so instead of the needle going in at a 90-degree angle, the subcutaneous injection angle is at 45 degrees so that it pierces the skin but not the muscle tissue

Edaravone (EDA) is a highly biologically active free radical scavenger known for its antioxidant, anti-inflammatory, and neuroprotective effects (SRIRAM et al., 2016)