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This tetrapeptide, also known as KEDG (Lys-Glu-Asp-Gly), is among numerous short signaling peptides discovered and studied by Professor Vladimir Khavinson, a Russian gerontologist and academician [29]

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GLP-1RAs and muscle GLP-1RAs and Muscle Atrophy In previous experiments, exendin-4 (Ex-4) inhibited the expression of myostatin (MSTN), atrophy-factor F-box only protein 32 (atrogin-1) and muscle ring finger protein 1 (MuRF-1) in dexamethasone-treated C2C12 myotubes