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It has been reported that proline biosynthesis could contribute to GSH synthesis

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In summary, LSECs are integral to various aspects of ALD pathogenesis, including ethanol metabolism, oxidative stress regulation, inflammation, fibrosis and potentially regeneration

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The Most Studied Pathways, being the most extensively researched and containing a larger number of identified pathway genes, along with Gene-Associated Pathways, which are closely related to AD pathology-associated genes and often focused on drug development, are both more likely to yield natural products with multiple gene targets