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The most important adverse effects of LDL-apheresis include: hypotension, abdominal pain, nausea, vomiting, vertigo and headache, hypocalcaemia, iron deficiency anaemia, allergic reactions, haemolysis, and thrombocytopenia

The CagriSema program, combining cagrilintide with semaglutide, has demonstrated: 15.1% mean body weight reduction at 32 weeks in REDEFINE 1 trial Approximately 15-17% weight loss in various phase 3 timepoints Superior outcomes compared to semaglutide monotherapy Manageable safety profile with expected GI side effects Cagrilintide 10mg remains an important research tool for scientists exploring amylin analogue applications