Rebecca Hunton Mar 13, 2025 2 min read Accutane (isotretinoin) can be an effective treatment for severe acne, but because it is a powerful medication, its important to support your skin, liver, gut, and overall health while taking it
This is likely an important mechanism underlying GLP-1 analogues effects not only on the attenuation of postprandial glucose and insulin excursions, but also the enhancement of satiety and reduction in energy intake
But to me it's a relatively minor leap to say if we know these things based on hemoglobin A one C to be true, it's very likely that they're going to be true based on capturing more accurate data with the continuous glucose monitor
Side Effects: Sedation Parkinsonism symptoms QT prolongation (may be significant if taking with drugs inhibiting CYP3A4/5 or 2D6) Pharmacokinetics: undergoes rapid hepatic metabolism involving carbonyl reductase and CYP2D6 to 2 deuterated active metabolites -dihydrotetrabenazine (-HTBZ) and -dihydrotetrabenazine (-HTBZ), with eventual renal elimination of metabolites the -HTBZ and -HTBZ metabolites are primarily responsible for the pharmacological & therapeutic effects produced by the parent prodrug twice a day dosing effect half life 9.4 hours (Schneider et al, 2021) HT: Resistant Hypertension
These bacteria ferment carbohydrates prematurely, leading to gas production, inflammation, and malabsorption
