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Polyamines, primarily putrescine, spermidine, and spermine, are abundant in the digestive system and are derived from food or biosynthesized by the host and bacteria

Cytoprotective effects against viruses like SARS-CoV-2 could be enhanced by sulforaphane, an isothiocyanate abundant in cruciferous vegetables, since sulforaphane has been found to be a powerful activator of the Nrf2 pathway by increasing Nrf2-regulated cellular antioxidant response such as induction of NAD(P)H: quinone oxidoreductase 1, glutamate-cysteine ligase (-glutamyl cysteine synthetase) and glutathione (Theodore et al., 2008

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