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Short-term studies havent found acute safety issues, but because there are no long-term human studies, its safety over time is unknown

GSSG can subsequently be reduced back to GSH by glutathione reductase, which is coupled to NADPH as the electron donor

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In case BM samples were further processed for a scRNA-Seq, a density gradient centrifugation was then conducted using Histopaque 1077/1119 (Sigma-Aldrich), following the manufacturers protocol