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P = 0.004), 1.63 at week 8 (95% CI, 1.11 to 2.39
This is important, as 5mC and 5hmC can have different effects on gene regulation: 5mC at CpG islands is associated with reduced transcription, while 5hmC in intergenic regions is linked to increased gene expression 126
Even though 68% of adult smokers say they want to stop, less than 10% of them are successful in their efforts
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