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The resulting residual confounding suggests that the apparent association between EC use and health outcomes could in reality be partly, or perhaps fully, explained by cumulative smoking history

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108 Smoking Damages Brain Cells Smoking has been found to have a negative impact on brain cells, increasing the risk of devastating diseases such as amyotrophic lateral sclerosis (Lou Gehrigs disease) and Alzheimers

The symptoms are often detected at the time when the smokers health condition is already chronic

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