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Interventions such as chondroitinase ABC and neutralizing antibodies against myelin inhibitors have demonstrated modest success in facilitating axonal sprouting and synaptic reorganization [276]
For example, melatonin, -endorphin, and phenylpropanolamine all lower seizure thresholds within a day
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In a depleted body, the ROS accumulate, which can cause immediate mitochondrial damage and trigger the severe, delayed symptom flares characteristic of PEM
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