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And those who stop taking them typically regain two-thirds of the weight they lost within a year

However, patients and clinicians should understand that pharmacokinetic steady state does not necessarily correspond to maximal therapeutic benefit

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Obstet Gynecol Int 2013:859619

The 2024 Vanderbilt finding that a diastolic BP increase greater than 17 mmHg during late phase 2 of the Valsalva maneuver identifies patients with high sympathetic nerve activity is a simpler, office-based alternative to plasma catecholamine testing