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The effect of dapagliflozin on fasting glucose was 57% relative to that of semaglutide, whereas the effect of dapagliflozin on 2-h glucose was only 38% compared with that of semaglutide (Table 2 and Supplementary Table 4)

Currently available GLP-1 receptor agonists in the United States include exenatide (Byetta, Bydureon BCise), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), semaglutide (Ozempic, Wegovy, Rybelsus), and tirzepatide (Mounjaro, Zepbound), though tirzepatide is technically a dual GIP/GLP-1 receptor agonist

Your clinician will work with you to find what feels best, balancing comfort, side effects, and results

Better Blood Sugar Control: Semaglutide helps the body release insulin when needed

For comparison, patients taking the maximum dose of Zepbound (10 mg to 15 mg) lost 20.9% after 72 weeks