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SURMOUNT-2 (NCT04657003) Study Title: "Tirzepatide Once Weekly for the Treatment of Obesity in People With Type 2 Diabetes" Status: Completed Phase: Phase 3 Enrollment: 938 participants Study Period: 2020-2022 Design: Randomized, double-blind, placebo-controlled Duration: 72 weeks Intervention: Tirzepatide 10/15 mg SC weekly vs

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Consequently, CYP3A4 protein synthesis is increased (Lehmann et al., 1998)