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KD treatment in patients with DKD resulted in more significant reductions in waist circumference, lean body mass, eGFR, as well as levels of insulin, HbA1c, fasting blood glucose, LDL-C, and IL-6 compared to those following a low-protein, low-salt diet, with modest increases in HDL-C and LDL-C levels [121]

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ET-1 mediates its effects through two receptors, ET A and ET B

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