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Further, we think second-quarter topics like ACA procedure headwinds, China competition, law of large numbers catching up to growth, and initiatives focused on lowering prices could all weigh on sentiment as they introduce some uncertainty around the P&Lcollectively, these might limit share upside in the next couple of quarters." "On balance, the quarter itself looked fine, though the combination of softer U.S

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Thirdly, glucagon receptor activation introduces an additional layer of metabolic complexity