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Energy deficits result in impaired smooth muscle cell contractility, reducing vascular regulation and leading to sustained vascular constriction and elevated blood pressure

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In some embodiments, an otic intervention is a surgical procedure including, by way of non-limiting examples, cochleostomy, labyrinthotomy, mastoidectomy, stapedectomy, stapedotomy, endolymphatic sacculotomy, tympanostomy, or the like

A detailed investigation of the functions and properties of cytotoxic ELOA might be used profitably in various biotechnological applications with the potential to specifically target undesirable cells [70]

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