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These strategies may involve diverse mechanisms in glial cells and neurons, including inhibition of apoptosis, reduction of excitotoxicity, suppression of neuroinflammation, enhancement of mitochondrial function, or promotion of neuronal regeneration [565, 566]

The strategy is then to mix and match amino acid residues from the three natural peptides, I call this a Frankenstein strategy, youre taking the pieces from here, pieces from there, says Gellman