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[14] mhra.gov.uk) or contact your local trading standards office

References Kwon Y, et al

Moreover, while NfL correlates with disease activity and long-term prognosis, it has not yet been validated as a surrogate endpoint in clinical trials, limiting its utility in regulatory routes

These shifts tend to happen early and provide a strong foundation for long-term progress

Conclusions The concept of the leaky gut, although used to explain the pathogenesis of many common diseases, should be rethought in terms of the available data that support the many means by which luminal substances cross the gut mucosal barrier

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