EGF acts primarily on keratinocytes at the epidermal level
By blocking NNMT, it shifts intracellular NAD+ and S-adenosylmethionine (SAM) levels, two cofactors tied to energy metabolism, redox balance, and gene regulation in laboratory models
Animal studies show no toxicity up to high doses, but human reports are anecdotal
At present, the prevailing GHK-Cu dosage protocol appears to be as follows: Daily Dosage: 1-2 mg of GHK-Cu
Sources: Clinical, Cosmetic, and Investigational Dermatology, September 2015, pages 463-470 Journal of the America Academy of Dermatology, November 2012, pages 1,103-1,024 Skin Research and Technology, August 2008, pages 376-380 Dermatologic Surgery, July 2005, pages 814-817 Canadian Family Physician, July 2006, pages 855-856 Dermatologic Surgery, April 1999, pages 311-315 *Please Note: due to supply chain this product will be shipping without the outer box *This product is a dietary supplement and is free from any drugs