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Your gut microbiome and digestive rhythm take time to rebalance, and reduced food intake (from appetite suppression) means less bulk moving through your system, which naturally leads to fewer and harder stools

Similarly, those scheduled for major surgery should discuss timing of GLP-1 injections or oral doses with their surgical team, as any medication affecting blood vessel function deserves consideration in perioperative planning

doi: 10.1111/nmo.13546 95 RaybouldHE

Although rapid changes can sometimes reveal underlying problems, weight loss generally reduces long-term pressure on spinal discs

Sexual health: Peptides like PT-141 address erectile function through melanocortin pathways