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Th17/Treg cells imbalance and their related cytokines (IL-17, IL-10 and TGF-) in children with autism spectrum disorder

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An additional mechanism by which bile acid induction of FXR reduces hepatic accumulation of toxic bile acids is by activation of the ABCB11 gene, which encodes the canalicular bile salt export pump (BSEP), allowing a higher rate of bile salt export from hepatocytes