Retatrutide is an investigational triple receptor agonist targeting GLP-1, GIP, and glucagon receptors, not yet licensed by the MHRA or EMA, with Phase 2 data showing substantial weight reduction over 48 weeks
In older patients, retatrutide weight loss may result in more skin laxity
Compounded vials let you draw any amount, which gives providers the ability to prescribe intermediate doses like 0.375 mg or 1.25 mg for patients who need a gentler microdosing approach
doi:10.1016/s0753-3322(02)00253-6 Djousse L, Biggs ML, Lemaitre RN, et al
Despite these numbers, GLP-1 drugs account for relatively small shares of total Medicaid spending and prescriptions, the report noted -- about 0.5% of all Medicaid prescriptions and 3.7% of gross Medicaid spending