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Relative contraindications requiring caution include active or suspected cancer (GHK-Cu promotes angiogenesis with concern about theoretically feeding tumors, though conflicting data shows documented anti-cancer gene expression effects requiring medical supervision), severe organ dysfunction (kidney or liver failure may slow peptide clearance), hemochromatosis or copper overload conditions, autoimmune disorders, and patients on immunosuppressants or blood thinners

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It is standard research practice to evaluate Certificates of Analysis (COAs) and source materials from facilities that utilize third-party analytical testing

38 GjurasinM.MiklicP.ZupancicB.PerovicD.ZarkovicK.BrcicL.et al (2010)