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India, often referred to as the diabetes capital of the world, represents a major market opportunity

"Development of PPAR-agonist GW0742 as antidiabetic drug: study in animals"

As implied by the terms, HFrEF represents HF where the left ventricular (LV) EF is markedly reduced (40% or lower), HFmrEF describes a mildly reduced LV EF of 40%49%, whereas in HFpEF the LV EF is preserved at around 50% or more

Some preclinical studies have found that the GLP-1 hormone may help prevent the buildup of tau tangles and amyloid plaques, which are associated with Alzheimers disease, but researchers stressed the need for more data

58, 87, 88 GLP-1R stimulation has demonstrated positive effects in rodent models of Alzheimers disease as well as Parkinsons disease (a degenerative disorder of dopaminergic neurons)