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This is a rare state where an internal short circuit or physical damage causes the battery to heat up uncontrollably

Reduced Lung Function: Chronic exposure to secondhand smoke during childhood can lead to long-term reductions in lung function and increase the risk of developing chronic obstructive pulmonary disease (COPD) later in life

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These individual variations in nicotine tolerance are at least in part due to the pharmacogenetics of Cytochrome P450 2A6 (CYP2A6), the hepatic enzyme primarily responsible for nicotine metabolism [18]