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AbbVie reported that ABBV-295 demonstrated clinically meaningful body weight reduction ranging from approximately 7.75% to 9.79% over the treatment period, while also showing a favorable tolerability profile with no serious adverse events reported

The UK product licences for weight management medications (Wegovy and Saxenda) specify that they should be used as part of a comprehensive weight management programme that includes diet and physical activity

the right femoral vein is catheterized (Abbocath catheter, T 22G x 32 mm) and perfused with a dilute solution (1%) of veterinary sodium pentobarbital

GSH depletion was apparent after all three treatments (Fig