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The android fat distribution pattern may be justified by hyperandrogenism, resulting in a vicious circle of central adiposity, hyperinsulinism, and metabolic aberrations ( Polycystic Ovary Syndrome (PCOS) PCOS is a recurrent reproductive endocrinological disorder that affects up to 20% of women of reproductive age globally ( 3 ovarian volume) ( The insulin-like growth factor-I receptor (IGF-IR) could also be involved in the mechanism of hyperandrogenism induced by hyperinsulinemia observed in PCOS patients

Conditions like PCOS (polycystic ovary syndrome) and thyroid problems can make it harder to lose weight

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