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According to the study, active smokers face a 2.4-fold greater risk of experiencing reflux esophagitis compared with people who have never smoked, while former smokers who accumulated more than 20 pack-years of smoking history face a risk increase factor of 2.5

Smoking becomes less pleasurable, and smokers may need to increase their intake to get their "reward." A smoker develops tolerance to these effects very quickly and requires increasingly higher levels of nicotine

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