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As a relatively new drug, tofacitinib carries a black triangle warning, denoting that patients require extra monitoring while taking it[102]

The findings underscore the potential of dietary interventions in modulating brain function in ASD and call for further research to elucidate the underlying mechanisms and optimize clinical practice

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PDGF is secreted by activated platelets, endothelial, epithelial, glial cells as well as inflammatory cells and it targets a broad spectrum of cell type including, fibroblasts, pericytes, smooth muscle cells, glial cells or mesangial cells [140]