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To address these challenges and elevate oridonins therapeutic potential, we opted for liposomes comprising maleimide polyethylene glycol (PEG) for nano-delivery [30, 31]

and compared dblGATA-1 4get C57BL/6 mice and 4get C57BL/6 mice (D50)

10.1016/j.jconrel.2023.11.030 63 HuaL.LeiT.QianH.ZhangY.HuY.LeiP

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This leads to the accumulation of glucose and other intermediate metabolites of this pathway and is shifted to other alternative pathways of glucose metabolism, together with increased production of end products of enhanced glycosylation