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Recently, there have been several MR studies on the association between T2D and SA, such as the study by Shen et al

Homocysteine accumulates in the blood when there is inadequate folate and/or vitamin B 12 for effective functioning of the methionine synthase enzyme (see Function)

Methionine serves as a precursor for S-adenosylmethionine (SAM), an important biological methyl donor, while B vitamins participate in numerous enzymatic reactions involved in amino acid metabolism, nucleic acid synthesis, and cellular energy production

I pay attention to that because it tells me they are not just manufacturing a single trending format