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Denlinger-Apte, Ph.D., M.P.H., from the Wake Forest University School of Medicine in Winston-Salem, North Carolina, and colleagues examined whether people who smoke may increase their smoking to compensate for the reduced nicotine levels when smoking VLNCs for prolonged periods

This happens because your digestive system has adapted to regular cannabinoid stimulation, and removing that stimulation can temporarily slow gut motility

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A subsequent paper from this project makes it clear that dissatisfaction with these cigarettes was the major predictor of cheating by smoking conventional cigarettes, and this was found in the large majority (78 percent) of participants

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