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Molecular speciation and dynamics of oxidized triacylglycerols in lipid droplets: mass spectrometry and coarse-grained simulations

Coma and metabolic acidosis early in severe acute paracetamol poisoning

Body weight gain was significantly attenuated from day 30 to day 60 in the rotenone-exposed group, compared with the vehicle-treated group

Results Establishment of CRC Drug-Tolerant Persister Cell Models While modeling the response to the chemotherapeutic drug 5-FU in the CRC cell line HCT116, which has exquisite sensitivity, we observed that the vast majority of the cells were killed within 9 days of exposure to the drug at a concentration 10-fold higher than the IC 50 value ( Figure 1A )

The 68 hour half-life makes KLOW suitable for once-daily administration without significant accumulation, while the 7296 hour functional duration allows every-other-day dosing in maintenance protocols