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On the other hand, if a patient is fully reliant on the medication and experiences little to no hunger, those fluctuations may be less noticeable

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The studies show that higher levels of either an agonist (something that stimulates the receptor) or an antagonist (something that blocks the receptor) alter the addictive response.[ref] DRD3 receptor: The DRD3 receptor is found in the ventral striatum and other limbic areas in the brain

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By increasing the availability of these neurotransmitters, tesofensine may influence the brains reward and appetite centers, potentially modulating the disordered eating behaviors associated with eating disorders