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They have a tremendous amount of excess skin, requiring multiple [skin-removal] surgeries. But the 50% losing far less weightmore like 20 to 30 poundsstill have skin laxity and volume changes in their faces, breasts, and bodies

Diabetes Metab J 2025;49:333-347

Low Blood Sugar (Hypoglycemia) : Although less common, semaglutide can cause low blood sugar, especially if you are taking other diabetes medications

JAMA Internal Medicine analyzed 18,386 matched pairs in a retrospective EHR cohort and found tirzepatide at 15.3% and semaglutide at 8.3% weight loss at 12 months

The most appropriate medication is prescribed based on your individual needs, medical history, and weight loss goals