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Its primary actions include: Inhibiting the reuptake of dopamine and noradrenaline in the central nervous system Minimal effect on serotonin pathways, distinguishing it from most other antidepressants Potential appetite suppression as a secondary effect, though this is not its primary indication Reducing nicotine cravings through dopaminergic pathways Bupropion is metabolised primarily in the liver by the CYP2B6 enzyme system, producing active metabolites
For women, menstrual changes deserve attention
History of medullary thyroid cancer or MEN2 Pregnancy or breastfeeding Severe GI disorders (gastroparesis) Certain endocrine conditions Allergy to GLP-1 medications Appetite reduction begins within the first 12 weeks
To qualify for Ozempic for weight loss , you generally need to meet specific BMI criteria
More serious concerns are less common but important
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