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The condition often progresses gradually, making early detection challenging without proper testing
Seventeen studies were conducted in hospital settings, and the remaining 8 in university hospital settings
Despite these protective mechanisms, elevated serum B12 levels (hypercobalaminaemia) can occur and may indicate underlying health conditions rather than simple overconsumption
This is especially important for patients with absorption issues such as those with digestive conditions, low stomach acid (common with aging), or MTHFR gene variants who cannot adequately absorb B12 from food or oral supplements
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