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GSH biosynthesis occurs exclusively in the cytosol via a two-step ATP-dependent reaction catalysed sequentially by two enzymes: gamma-glutamylcysteine synthetase (GCL also referred to as gamma-glutamylcysteine ligase, comprising the catalytic GCLC subunit and regulatory GCLM subunit), which catalyses the rate-limiting first step of joining glutamate and cysteine
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The KLOW peptide blend is formulated as a controlled laboratory compound used in peptide-based scientific investigations
, the role of rituximab in T1D was evaluated
Savini I, Catani MV, Evangelista D, Gasperi V, Avigliano L
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