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A more strategic clinical decision is to maintain the GLP-1 at a tolerable maintenance dose to control appetite, and introduce a complementary mechanism

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Always follow your healthcare provider's specific instructions for dosing and administration

Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition

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