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And side effects are cited as a reason why over half of people stop taking GLP-1s within one year of starting

If the patients skin type is Fitzpatrick Skin Type 4-6, has a history of hormonal patches, or has been sunburned before treatment, it will increase the risk of hyperpigmentation

Growth Hormone Products Amplified effects when combined Increased risk of side effects Requires professional oversight 3

SKINS ANATOMY Our skin has many layers, and melanocytes that create pigment are found at the bottom of our epidermis layer

Methods Study searches The protocol was registered on PROSPERO (CRD CRD420251074781), and we carried out this meta-analysis in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines [15]