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A major study published in the New England Journal of Medicine found that people using tirzepatide lost 20.2% of their body weight on average, while those using semaglutide lost 13.7%

Sugar alcohols in particular are prime offenders because they are poorly absorbed and ferment rapidly, which is why combining semaglutides slowed digestion with those sweeteners often produces severe bloating and prolonged discomfort

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Each dosage increase should take place over several weeks to monitor the bodys response and find the effective dose that balances benefits with tolerability