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A changing ecosystem across age, environment, diet, and diseases
In the UK, several GLP-1 receptor agonists are licensed by the Medicines and Healthcare products Regulatory Agency (MHRA), each with specific indications: semaglutide (Ozempic for type 2 diabetes, Wegovy for weight management), dulaglutide (Trulicity for type 2 diabetes), and liraglutide (Victoza for type 2 diabetes, Saxenda for weight management)
Predisposing factors to CMD like DM, obesity, hypertension, dyslipidaemia, and ageing result in vascular dysfunction partly through oxidative stress [64]
[8] The typical symptoms involve a combination of pain, loss of nerve function, and/or a palpable (or radiographically apparent) mass affecting a peripheral nerve